Jigsaw is proprietary software for creating analysis-ready datasets for research using healthcare data from all sources. Examples of data include claims data from Medicare and SEER-Medicare, as well as proprietary claims and EMR data sources commonly used in healthcare research. Jigsaw allows users to create arbitrarily complex algorithms to identify the information of interest from the data and to compose an entire protocol from these algorithms (e.g., inclusion and exclusion criteria, baseline variables, outcome variables, etc.). Jigsaw uses the user-created protocol to generate all of the SQL necesary to pull the relevant data, and Jigsaw organizes the data into files for research purposes. For a 7-minute demo, please see this YouTube link.